The findings of this review are thought to be guiding clinicians and researchers working with individuals with Parkinson's Disease. In this review, reliable and valid outcome measures for evaluating functional mobility and activity limitation in individuals with Parkinson's disease are presented, and it was found that the number of studies which compare these measures are limited. For this purpose, Pubmed, Google Scholar, Science Direct databases have been searched using the related keywords, and all relevant studies in the literature have been reviewed until July 1, 2019. The aim of this study is to review the literature about the most appropriate patient-reported outcome measures and performance-based measures to evaluate functional mobility and activity limitation in individuals with Parkinson Disease. In order to achieve a patient-centered rehabilitation in Parkinson’s Disease, when assessing perceived difficulty in everyday life, performance-based measures should be complemented with patient-reported outcome measures. These disturbances negatively affect individuals' quality of life by causing activity and function limitations. In Parkinson’s Disease, bradykinesia, resting tremor, rigidity and postural instability are of the main symptoms, and cause posture, balance and gait disturbances. Parkinson’s Disease which is characterized by motor and non-motor symptoms, is the second most common neurodegenerative disease after Alzheimer’s disease. Bu derleme bulgularının Parkinsonlu bireylerle çalışan klinisyen ve araştırmacılara yol gösterici olacağı düşünülmektedir.Īnahtar Kelimeler: Parkinson hastalığı günlük yaşam aktiviteleri hareket kısıtlılığı sonuç ölçümleri yürüyüş Bu derlemede, Parkinsonlu bireylerde fonksiyonel mobilite ve aktivite limitasyonunu değerlendirmeye yönelik güvenilir ve geçerli sonuç ölçümleri sunulmuş, bunların karşılaştırıldığı çalışmaların ise sayıca kısıtlı olduğu görülmüştür. Bu amaçla Pubmed, Google Scholar, Science Direct veri tabanları ilgili anahtar kelimeler kullanılarak taranmış, 1 Temmuz 2019 tarihine kadar literatürde yer alan konuyla ilgili tüm çalışmalar gözden geçirilmiştir. Bu çalışmanın amacı, Parkinsonlu bireylerde aktivite limitasyonu ve fonksiyonel mobiliteyi değerlendiren en uygun hasta bildirimli ve performansa yönelik sonuç ölçümlerini derlemektir. Parkinson hastalığında hasta merkezli rehabilitasyonu sağlamak için günlük yaşam aktivitelerinde algılanan zorlukların değerlendirilmesi aşamasında performansa yönelik ve hasta bildirimli sonuç ölçümlerinin bir arada ele alınması büyük önem taşımaktadır. Bu bozukluklar aktivite ve fonksiyon kısıtlılıklarına neden olarak bireylerin yaşam kalitesini olumsuz yönde etkilemektedir. Parkinson hastalığında bradikinezi, istirahat tremoru, rijidite ve postüral instabilite başlıca belirtilerdendir ve postür, denge ve yürüyüş bozukluklarına yol açarlar. Motor ve motor olmayan semptomlarla karakterize Parkinson hastalığı Alzheimer hastalığından sonra ikinci en sık görülen nörodejeneratif hastalıktır. (Patient-Reported and Performance-Based Outcome Measures for Functional Mobility and Activity Limitation in Individuals with Parkinson's Disease: A Review Study) Parkinsonlu Bireylerde Fonksiyonel Mobilite ve Aktivite Limitasyonuna Yönelik Hasta Bildirimli ve Performansa Dayalı Sonuç Ölçümleri: Bir Derleme Çalışması The findings suggest that the Timed Up & Go test may be an accurate assessment tool to identify those at risk for falls. Additional analysis revealed a proposed cut score of 11.5 seconds for discrimination of those who did or did not fall. The secondary model in which the question of whether the effect of Timed Up & Go test was invariant across disease severity demonstrated 75% of participants were accurately classified as a faller or nonfaller. The estimated models in the imputed data sets represented a significant improvement above chance (χ(2) range, 531.29-542.39, P<.001), suggesting that 74% of participants were accurately classified as a faller or nonfaller. The initial model examined the prediction of falls from the Timed Up & Go test, adjusting for all study covariates. The chief independent variable was the Timed Up & Go test. The primary outcome measure for this study was falls. From these, 884 were excluded because of a lack of crucial information (age, diagnosis, presence of deep brain stimulation, disease duration, inability of performing the Timed Up & Go test without assistance) at the time of testing, leaving 2097 patients included in the analysis. Sixteen participating National Parkinson's Foundation Centers of Excellence.Ī query yielded a total of 2985 records (1828 men and 1157 women). To investigate the ability of the Timed Up & Go test to identify patients with Parkinson's disease at risk for a fall.
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